Conchita Delcroix-Gomez
University of Limoges, France
Title: Smoking, pregnancy and vulnerability (SPV): Intra-uterine growth retardation (IUGR) of toxic origin can it be influenced by the early cessation
Biography
Biography: Conchita Delcroix-Gomez
Abstract
Maternal smoking has a negative impact on the evolution of pregnancy, fetal development and perinatal indicators.
The objective of the study is to demonstrate that early smoking cessation influences the onset of intrauterine growth retardation and the occurrence of complications such as gestational diabetes, preeclampsia, the threat of premature birth and finally premature delivery.
This study is a prospective, multicenter cohort, carried out between November 2013 and March 2016, in four French maternity hospitals. This research was classified at low risk by the Ethics Committee of the motherchild hospital of the University of Limoges in France, March 2013. Nine hundred twenty pregnant women who smoked were included in our study. The timing of smoking cessation during pregnancy (1st, 2th, 3th trimester) was filled as well as the type of care. Smoking cessation was defined if the pregnant woman declared zero cigarettes smoked per day and obtained a measurement of CO in the exhaled air < at 3 ppm. The rate of cessation of smoking during pregnancy was 31.4%. The average weight of the newborn mother was decreased by 433 g with a p<0.0001 associated with a decrease of 14.19% of the mean percentile (p<0.018): average weight of the newborn mother who stopped smoking was 3,350 g±485, with respective percentiles of 45.98%
Conclusion: <span segoe="" ui",="" roboto,="" "helvetica="" neue",="" arial,="" "noto="" sans",="" sans-serif,="" "apple="" color="" emoji",="" "segoe="" ui="" symbol",="" emoji";="" font-size:="" 14.4px;="" background-color:="" rgb(255,="" 255,="" 255);"="" style="color: rgb(33, 33, 33);">Early cessation of smoking influences the number of intrauterine growth retardation of toxic origin below the 10th percentile.